Correlation of CTSD, P63, and Ki67 Expressions with Risk Assessment of Oesophageal Squamous-Cell Carcinoma

Objective. Creatine kinase (CK), cathepsin D (CTSD), Ki67, and tumour protein 63 (p63) have been proven to participate in the growth of some cancers. However, available literature suggested paucity data on their involvement oesophageal squamous-cell carcinoma (ESCC) development. Methods. We ascertained presence CK, CTSD, p63 expressions ESCC demonstrate association between differentiation abovementioned proteins. collected related information 48 patients prior division into well poor groups, which were analysed retrospectively. Positive rates expression evaluated via immunohistochemistry. The proteins that expressed positively all cases selected. Comparison within two groups was done analyse correlation expression. Results. observed p63, Ki67 significantly highly poorly differentiated with ESCC. Conclusions. This finding may suggest involved progression, evidentially serve as potential markers early identification risk assessment